Tirzepatide dosage chart in units
Units to draw = dose (mg) ÷ concentration (mg/mL) × 100. A 5 mg dose is 50 units from a 10 mg/mL vial but 25 units from a 20 mg/mL vial, so find the column that matches your vial's label.
Label dosing schedule
This is the titration in the FDA labels for Zepbound (weight management) and Mounjaro (type 2 diabetes). Both are injected once a week.
| Step | Weekly dose | Notes |
|---|---|---|
| Start, weeks 1–4 | 2.5 mg | Starting dose only, not for maintenance |
| Then | 5 mg | Can be a maintenance dose |
| If needed | 7.5 mg | Increase by 2.5 mg after at least 4 weeks on the current dose |
| If needed | 10 mg | Can be a maintenance dose |
| If needed | 12.5 mg | Increase by 2.5 mg after at least 4 weeks |
| Maximum | 15 mg | Highest dose on the label |
Units to draw for each dose
Find your vial's concentration across the top and your dose down the side. Values are units on a U-100 insulin syringe (100 units = 1 mL).
| Weekly dose | 5 mg/mL | 10 mg/mL | 15 mg/mL | 17 mg/mL | 20 mg/mL | 30 mg/mL |
|---|---|---|---|---|---|---|
| 2.5 mg | 50 | 25 | 16.7 | 14.7 | 12.5 | 8.3 |
| 5 mg | 100 | 50 | 33.3 | 29.4 | 25 | 16.7 |
| 7.5 mg | 150 | 75 | 50 | 44.1 | 37.5 | 25 |
| 10 mg | 200 | 100 | 66.7 | 58.8 | 50 | 33.3 |
| 12.5 mg | 250 | 125 | 83.3 | 73.5 | 62.5 | 41.7 |
| 15 mg | 300 | 150 | 100 | 88.2 | 75 | 50 |
Greyed values are over 100 units (1 mL) and won't fit in one U-100 syringe. That dose isn't used with that vial strength; check your label.
The same doses in mL
| Weekly dose | 5 mg/mL | 10 mg/mL | 15 mg/mL | 17 mg/mL | 20 mg/mL | 30 mg/mL |
|---|---|---|---|---|---|---|
| 2.5 mg | 0.5 | 0.25 | 0.167 | 0.147 | 0.125 | 0.083 |
| 5 mg | 1 | 0.5 | 0.333 | 0.294 | 0.25 | 0.167 |
| 7.5 mg | 1.5 | 0.75 | 0.5 | 0.441 | 0.375 | 0.25 |
| 10 mg | 2 | 1 | 0.667 | 0.588 | 0.5 | 0.333 |
| 12.5 mg | 2.5 | 1.25 | 0.833 | 0.735 | 0.625 | 0.417 |
| 15 mg | 3 | 1.5 | 1 | 0.882 | 0.75 | 0.5 |
Greyed values are over 1 mL, more than one U-100 syringe holds.
Find your vial's concentration
Concentration is the amount of tirzepatide in each mL of liquid. If your label lists mg and mL separately, divide them:
- Zepbound single-dose vials hold the dose in 0.5 mL, so the concentration is twice the dose: a 2.5 mg vial is 5 mg/mL, a 5 mg vial is 10 mg/mL, a 7.5 mg vial is 15 mg/mL. The whole vial is one dose of 50 units.
- 30 mg in 3 mL = 10 mg/mL. 30 mg in 2 mL = 15 mg/mL.
- 60 mg in 3 mL = 20 mg/mL. 60 mg in 2 mL = 30 mg/mL.
- 17 mg/mL appears on some pharmacy labels. Use the 17 mg/mL column directly.
Any other combination: use the tirzepatide units calculator, which accepts either the mg/mL or the vial amount and liquid volume.
Reading the result on a syringe
Some answers fall between the lines, such as 16.7 units for 2.5 mg at 15 mg/mL. A 0.3 mL syringe is marked every unit; a 1 mL syringe every 2 units. Use the smallest syringe that holds the dose, and ask your pharmacist how to round when the number isn't on a line. The insulin syringe guide shows the markings on each size.
Why charts online disagree
Most tirzepatide charts you'll find are handouts from a single clinic, written for the one vial strength that clinic dispenses. Used with a different vial they give the wrong number of units, even though the mg doses are identical. That's why this chart lists units by concentration instead of one column.
Questions
How many units is 2.5 mg of tirzepatide?
25 units at 10 mg/mL, 50 units at 5 mg/mL, about 16.7 units at 15 mg/mL and 12.5 units at 20 mg/mL. Check the concentration on your vial before using any chart.
How many units is 5 mg of tirzepatide?
50 units at 10 mg/mL, about 33.3 units at 15 mg/mL, about 29.4 units at 17 mg/mL and 25 units at 20 mg/mL.
What concentration is a 30 mg tirzepatide vial?
It depends on how much liquid is in it. 30 mg in 3 mL is 10 mg/mL; 30 mg in 2 mL is 15 mg/mL. Your pharmacy label should state the mg/mL. If it doesn't, ask before using the vial.
What is the starting dose of tirzepatide?
The Zepbound and Mounjaro labels start at 2.5 mg once weekly for 4 weeks. That dose is for starting treatment, not a maintenance dose. Your prescriber decides when and how to increase it.
Can I use this chart for Zepbound pens?
No. Pens are pre-set to a single dose and don't use syringe units. The units columns only apply when you draw from a vial with a U-100 syringe.